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Malesci A Laghi L, Bianchi P, Delconte G, Randolph A, Torri V, Carnaghi C, Doci R, RosatiR, Montorsi M, Roncalli M, Gennari L, Santoro A (2007) Reduced likelihood of metastases inpatients with microsatellite-unstable colorectal cancer. Even if impacted cerumenis not resolved by using a softener, such agents generallyfacilitate removal by subsequent syringing or curettage.The effectiveness of irrigation methods or mechanicalremoval is equivocal based on available data (Clegg et al.,2010)

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Deep tissue cultures may be of interest when they aretaken preoperatively in those patients with severe DFI associated with DFO thatrequire surgical debridement.
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